|
KMID : 0363320080290041075
|
|
Journal of Korean Oriental Internal Medicine
2008 Volume.29 No. 4 p.1075 ~ p.1082
|
|
|
Comparative Study of Natural Killer Cell Activity after Red Ginseng Medication on Rat
|
|
Im Ju-Hyuk
Cho In-Young
Min Kyoung-Yoon
Lee Hae-Young
Kim Seul-Ji
Park Young-Ju
Ryu Jae-Hwan
Lee Beom-Joon
Kim Sung-Wook
Joo Il-Woo
|
|
|
Abstract
|
|
|
Objectives: The purpose of this experiment is comparing the difference on natural killer cell activity through Korean red ginseng and Chinese red ginseng by 51Cr release assay.
Methods: Thirty rats were equally divided into a Korean red ginseng group, a Chinese red ginseng group and a control group. Korean and Chinese red ginseng were administrated to the rats at 200mg daily for a weak, while 0.9% normal saline was given to the control. Percent specific lysis (PSL) and lytic units (LU) were calculated from spleen cells by 51Cr release assay.
Results: Percent specific lysis of the Korean red ginseng group was significantly higher than that of the control in the ratio of 100:1, effector cell:target cell (p<0.05). Percent specific lysis of Korean red ginseng group was also significantly higher than that of the Chinese red ginseng group in the ratio of 25:1, effector cell:target cell (p<0.05). Chinese red ginseng showed no effect on NK cell activity.
Conclusions: These findings suggest that Korean red ginseng improves immunologic function and shows superior effects than Chinese red ginseng.
|
|
|
KEYWORD
|
|
|
Panax, Natural Killer Cells, Immunologic Cytotoxicity Tests
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|